Zhong V. W,, Van Horn L., Cornelis, M. C., Wilkins, J. T., Ning, H., Carnethon, M. R., et al.
185
Yes
From the source: "This study was supported by a postdoctoral fellowship to Dr Zhong from the American Heart Association Strategically Focused Research Networks (14SFRN20480260; principal investigator, Greenland). The Lifetime Risk Pooling Project was supported by the National Institutes of Health/National Heart, Lung, and Blood Institute (R21 HL085375) and by the Northwestern University Feinberg School of Medicine. The Jackson Heart Study is supported and conducted in collaboration with Jackson State University (HHSN268201300049C and HHSN268201300050C), Tougaloo College (HHSN268201300048C), and the University of Mississippi Medical Center (HHSN268201300046C and HHSN268201300047C), contracts from the National Heart, Lung, and Blood Institute, and the National Institute for Minority Health and Health Disparities."
From the source: "Dr Wilkins reported receiving consulting fees from NGM Biopharmaceuticals (Modest). Dr Mentz reported receiving research support from Akros, Amgen, AstraZeneca, Bayer, GlaxoSmithKline, Gilead, Luitpold, Medtronic, Merck, Novartis, Otsuka, and ResMed; honoraria from Abbott, Amgen, AstraZeneca, Bayer, Janssen, Luitpold Pharmaceuticals, Medtronic, Merck, Novartis, and ResMed; and serving on an advisory board for Amgen, AstraZeneca, Luitpold, Merck, Novartis and Boehringer Ingelheim. No other disclosures were reported."
This study pools the data of six prospective US studies and reports that people with higher dietary cholesterol intake are at greater risk of cardiovascular diseases (CVD) and death. However, the type of cholesterol containing foods explained this association, specifically, consuming eggs, unprocessed red meat, and processed meat. Strengths of this study are the large study population (29 615 participants ) and considerable follow-up time (approximately 17 years) as well as the precise breakdown of potential confounding factors and other known risk factors. Weaknesses of this study are the reliance on self-reports as the single measuring factor for dietary cholesterol. According to the authors, given the dose-response relationship between cholesterol and CVD among US adults, the results should be considered by dietary guidelines.
